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Western blot analysis of extracts of rat skeletal muscle, using Lipin 1 antibody (A8486) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
Lipin 1 Rabbit pAb
Catalog No：AB-A8486
Manufacturer：ABclonal
Synonyms：LPIN1;PAP1;lipin 1
Applications：WB
Reactivity：Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | Lipin 1 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes a magnesium-ion-dependent phosphatidic acid phosphohydrolase enzyme that catalyzes the penultimate step in triglyceride synthesis including the dephosphorylation of phosphatidic acid to yield diacylglycerol. Expression of this gene is required for adipocyte differentiation and it also functions as a nuclear transcriptional coactivator with some peroxisome proliferator-activated receptors to modulate expression of other genes involved in lipid metabolism. Mutations in this gene are associated with metabolic syndrome, type 2 diabetes, and autosomal recessive acute recurrent myoglobinuria (ARARM). This gene is also a candidate for several human lipodystrophy syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their full-length structures have not been determined. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 741-890 of human Lipin 1 (NP_663731.1). |
| Gene ID: | 23175 |
| Swiss prot: | Q14693 |
| Molecular weight: | 50kDa/98kDa/99-107kDa |
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