CLOZAPINE N-OXIDE [Cas No. 34233-69-7]
Catalog No:TA-T4494
Manufacturer:TargetMol
CAS No.:34233-69-7
Formula:C18H19ClN4O
MWt:342.82
€43,00 – €607,00
Name: | CLOZAPINE N-OXIDE |
Category: | Biochemicals |
Description: | Clozapine N-oxide is a major metabolite of clozapine that can be detected in the earliest excretion time interval after clozapine administration [1]. It is produced by the action of cytochrome P450 (CYP) isoforms CYP1A2 and CYP3A4, whose activities, in turn, can be affected by drugs and disease [2]. Clozapine N-oxide is normally biologically inactive. However, it can be used in designer receptor exclusively activated by designer drugs, also known as DREADDs, technology to modulate synthetic receptors in vivo [3]. |
Pathway: | GPCR/G Protein |
Target: | 5-HT Receptor |
Receptor: | 5-HT |
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