LIN28B Rabbit pAb
Catalog No:AB-A12958
Manufacturer:ABclonal
Synonyms:LIN28B;CSDD2
Applications:WB,IF
Reactivity:Human
Host:Rabbit
Conjugate:No
€65,00 – €325,00
Product Name: | LIN28B Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | The protein encoded by this gene belongs to the lin-28 family, which is characterized by the presence of a cold-shock domain and a pair of CCHC zinc finger domains. This gene is highly expressed in testis, fetal liver, placenta, and in primary human tumors and cancer cell lines. It is negatively regulated by microRNAs that target sites in the 3′ UTR, and overexpression of this gene in primary tumors is linked to the repression of let-7 family of microRNAs and derepression of let-7 targets, which facilitates cellular transformation. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 161-250 of human LIN28B (NP_001004317.1). |
Gene ID: | 389421 |
Swiss prot: | Q6ZN17 |
Molecular weight: | 19kDa/27kDa |
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