Western blot analysis of extracts of various cell lines, using LIN28B Rabbit mAb (A9524) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 3min.
LIN28B Rabbit mAb
Catalog No:AB-A9524
Manufacturer:ABclonal
Synonyms:CSDD2
Applications:WB,IHC
Reactivity:Human
Host:Rabbit
Conjugate:No
€65,00 – €485,00
Product Name: | LIN28B Rabbit mAb |
Category: | Monoclonal Antibodies |
Description: | The protein encoded by this gene belongs to the lin-28 family, which is characterized by the presence of a cold-shock domain and a pair of CCHC zinc finger domains. This gene is highly expressed in testis, fetal liver, placenta, and in primary human tumors and cancer cell lines. It is negatively regulated by microRNAs that target sites in the 3' UTR, and overexpression of this gene in primary tumors is linked to the repression of let-7 family of microRNAs and derepression of let-7 targets, which facilitates cellular transformation. [provided by RefSeq, Jun 2012] |
Immunogen: | A synthesized peptide derived from human LIN28B |
Gene ID: | 389421 |
Swiss prot: | Q6ZN17 |
Molecular weight: | 32kDa |
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