Western blot analysis of extracts of mouse pancreas, using LIN28A antibody (A6034) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
LIN28 Rabbit pAb
Catalog No:AB-A6034
Manufacturer:ABclonal
Synonyms:LIN28A;CSDD1;LIN-28;LIN28;ZCCHC1;lin-28A
Applications:WB,IF
Reactivity:Human,Mouse
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | LIN28 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a LIN-28 family RNA-binding protein that acts as a posttranscriptional regulator of genes involved in developmental timing and self-renewal in embryonic stem cells. The encoded protein functions through direct interaction with target mRNAs and by disrupting the maturation of certain miRNAs involved in embryonic development. This protein prevents the terminal processing of the LET7 family of microRNAs which are major regulators of cellular growth and differentiation. Aberrant expression of this gene is associated with cancer progression in multiple tissues. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 142-209 of human LIN28 (NP_078950.1). |
Gene ID: | 79727 |
Swiss prot: | Q9H9Z2 |
Molecular weight: | 22kDa |
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