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Western blot analysis of extracts of mouse pancreas, using LEP antibody (A1300) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
LEP Rabbit pAb
Catalog No：AB-A1300
Manufacturer：ABclonal
Synonyms：LEP;LEPD;OB;OBS;leptin
Applications：WB,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | LEP Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 22-167 of human LEP (NP_000221.1). |
| Gene ID: | 3952 |
| Swiss prot: | P41159 |
| Molecular weight: | 18kDa |
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