Western blot analysis of extracts of various cell lines, using LEF1 Rabbit mAb (A4473) at 1:500 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 3min.
LEF1 Rabbit mAb
Catalog No:AB-A4473
Manufacturer:ABclonal
Synonyms:LEF-1, TCF10, TCF1ALPHA, TCF7L3
Applications:WB
Reactivity:Human,Mouse
Host:Rabbit
Conjugate:No
€65,00 – €485,00
Product Name: | LEF1 Rabbit mAb |
Category: | Monoclonal Antibodies |
Description: | This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009] |
Immunogen: | A synthesized peptide derived from human LEF1 |
Gene ID: | 51176 |
Swiss prot: | Q9UJU2 |
Molecular weight: | 44kDa |
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