Western blot analysis of extracts of various cell lines, using LATS2 antibody (A16249) at 1:500 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 30s.
LATS2 Rabbit pAb
Catalog No:AB-A16249
Manufacturer:ABclonal
Synonyms:LATS2;KPM
Applications:WB,IHC
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | LATS2 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression. |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human LATS2 (NP_055387.2). |
Gene ID: | 26524 |
Swiss prot: | Q9NRM7 |
Molecular weight: | 120kDa |
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