Western blot analysis of extracts from normal (control) and RhoC knockout (KO) 293T cells, using RhoC antibody (A1062) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 300s.
[KO Validated] RhoC Rabbit pAb
Catalog No:AB-A1062
Manufacturer:ABclonal
Synonyms:RHOC;ARH9;ARHC;H9;RHOH9
Applications:WB,IHC,IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €485,00
Product Name: | [KO Validated] RhoC Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-193 of human RhoC (NP_001036144.1). |
Gene ID: | 389 |
Swiss prot: | P08134 |
Molecular weight: | 22kDa |
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