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Western blot analysis of extracts from normal (control) and PP2A-Abeta/PR65β/PP2A-Aβ/PR65β/PPP2R1B knockout (KO) 293T cells, using PP2A-Abeta/PR65β/PP2A-Aβ/PR65β/PPP2R1B antibody (A18089) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 60s.
[KO Validated] PP2A-Aβ/PR65β/PPP2R1B Rabbit pAb
Catalog No：AB-A18089
Manufacturer：ABclonal
Synonyms：PPP2R1B;PP2A-Abeta;PR65B
Applications：WB,IHC,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €485,00
| Product Name: | [KO Validated] PP2A-A尾/PR65尾/PPP2R1B Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes a beta isoform of the constant regulatory subunit A. Mutations in this gene have been associated with some lung and colon cancers. Alternatively spliced transcript variants have been described. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 468-667 of human PP2A-Abeta/PR65尾/PP2A-A尾/PR65尾/PPP2R1B (NP_859050.1). |
| Gene ID: | 5519 |
| Swiss prot: | P30154 |
| Molecular weight: | 52kDa/61kDa/66kDa/73kDa |
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