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Western blot analysis of extracts from normal (control) and PAK2 knockout (KO) HeLa cells, using PAK2 antibody (A18093) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 10s.
[KO Validated] PAK2 Rabbit pAb
Catalog No：AB-A18093
Manufacturer：ABclonal
Synonyms：PAK2;PAK65;PAKgamma
Applications：WB,IHC,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €485,00
| Product Name: | [KO Validated] PAK2 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-212 of human PAK2 (NP_002568.2). |
| Gene ID: | 5062 |
| Swiss prot: | Q13177 |
| Molecular weight: | 58kDa |
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