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Western blot analysis of extracts from normal (control) and NF-κB2 knockout (KO) HeLa cells, using NF-κB2 antibody (A18062) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 10s.
[KO Validated] NF-κB2 Rabbit pAb
Catalog No：AB-A18062
Manufacturer：ABclonal
Synonyms：CVID10;H2TF1;LYT-10;LYT10;NF-kB2;p100;p49/p100;p52
Applications：WB,IHC,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €485,00
| Product Name: | [KO Validated] NF-魏B2 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 690-899 of human NF-魏B2 (NP_002493.3). |
| Gene ID: | 4791 |
| Swiss prot: | Q00653 |
| Molecular weight: | 47kDa/96kDa |
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