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Western blot analysis of extracts of various cell lines, using MC1 Receptor Rabbit mAb (A11594) at 1：1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 3min.
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Western blot analysis of extracts of Mouse kidney, using MC1 Receptor Rabbit mAb (A11594) at 1：1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Enhanced Kit (RM00021).|Exposure time: 3min.
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Western blot analysis of extracts from normal (control) and MC1 Receptor knockout (KO) MCF7 cells, using MC1 Receptor antibody (A11594) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 180s.
[KO Validated] MC1 Receptor Rabbit mAb
Catalog No：AB-A11594
Manufacturer：ABclonal
Synonyms：CMM5, MSH-R, SHEP2
Applications：WB
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €485,00
| Product Name: | [KO Validated] MC1 Receptor Rabbit mAb |
| Category: | Monoclonal Antibodies |
| Description: | This intronless gene encodes the receptor protein for melanocyte-stimulating hormone (MSH). The encoded protein, a seven pass transmembrane G protein coupled receptor, controls melanogenesis. Two types of melanin exist: red pheomelanin and black eumelanin. Gene mutations that lead to a loss in function are associated with increased pheomelanin production, which leads to lighter skin and hair color. Eumelanin is photoprotective but pheomelanin may contribute to UV-induced skin damage by generating free radicals upon UV radiation. Binding of MSH to its receptor activates the receptor and stimulates eumelanin synthesis. This receptor is a major determining factor in sun sensitivity and is a genetic risk factor for melanoma and non-melanoma skin cancer. Over 30 variant alleles have been identified which correlate with skin and hair color, providing evidence that this gene is an important component in determining normal human pigment variation. [provided by RefSeq, Jul 2008] |
| Immunogen: | A synthesized peptide derived from human MC1 Receptor |
| Gene ID: | 4157 |
| Swiss prot: | Q01726 |
| Molecular weight: | 35kDa |
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Catalog No：AB-A0994
Manufacturer：ABclonal
Synonyms：HK2;HKII;HXK2;hexokinase-2
Applications：WB,IHC,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €485,00
Catalog No：AB-A0887
Manufacturer：ABclonal
Synonyms：BAF190;BAF190A;BRG1;CSS4;MRD16;RTPS2;SNF2;SNF2L4;SNF2LB;SWI2;hSNF2b;SMARCA4
Applications：WB,IHC,IF
Reactivity：Human
Host：Rabbit
Conjugate：No
€65,00 – €485,00
Catalog No：AB-A0735
Manufacturer：ABclonal
Synonyms：CSK
Applications：WB,IHC,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €485,00
Catalog No：AB-A0739
Manufacturer：ABclonal
Synonyms：NF2;ACN;BANF;SCH;merlin
Applications：WB,IF,IP
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €485,00
Catalog No：AB-A0533
Manufacturer：ABclonal
Synonyms：HK, HK1-ta, HK1-tb, HK1-tc, HKD, HKI, HMSNR, HXK1, hexokinase
Applications：WB,IHC,IF,IP
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €605,00
Catalog No：AB-A0229
Manufacturer：ABclonal
Synonyms：ERK;ERK-2;ERK2;ERT1;MAPK2;P42MAPK;PRKM1;PRKM2;p38;p40;p41;p41mapk;p42-MAPK;MAPK1
Applications：WB,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €485,00