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Western blot analysis of extracts of various cell lines, using GRK2 antibody (A1662) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.
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Western blot analysis of extracts from normal (control) and GRK2 knockout (KO) 293T cells, using GRK2 antibody (A1662) at 1:500 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 1s.
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Immunohistochemistry of paraffin-embedded rat brain using GRK2 Antibody (A1662) at dilution of 1:200 (40x lens).
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Immunohistochemistry of paraffin-embedded human esophageal cancer using GRK2 Antibody (A1662) at dilution of 1:200 (40x lens).
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Immunohistochemistry of paraffin-embedded mouse kidney using GRK2 Antibody (A1662) at dilution of 1:200 (40x lens).
[KO Validated] GRK2 Rabbit pAb
Catalog No：AB-A1662
Manufacturer：ABclonal
Synonyms：GRK2;ADRBK1;BARK1;BETA-ARK1
Applications：WB,IHC
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €485,00
| Product Name: | [KO Validated] GRK2 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 440-689 of human GRK2 (NP_001610.2). |
| Gene ID: | 156 |
| Swiss prot: | P25098 |
| Molecular weight: | 79kDa |
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