.jpg)
Western blot analysis of extracts of various cell lines, using GRK2 Rabbit mAb (A4443) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 3min.
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Western blot analysis of extracts from normal (control) and GRK2 knockout (KO) HeLa cells, using GRK2 antibody (A4443) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 30s.
[KO Validated] GRK2 Rabbit mAb
Catalog No：AB-A4443
Manufacturer：ABclonal
Synonyms：ADRBK1, BARK1, BETA-ARK1
Applications：WB,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €485,00
| Product Name: | [KO Validated] GRK2 Rabbit mAb |
| Category: | Monoclonal Antibodies |
| Description: | The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. [provided by RefSeq, Jul 2008] |
| Immunogen: | A synthesized peptide derived from human GRK2 |
| Gene ID: | 156 |
| Swiss prot: | P25098 |
| Molecular weight: | 80kDa |
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