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Western blot analysis of extracts of various cell lines, using FUS antibody (A5921) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 1s.
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Western blot analysis of extracts from normal (control) and FUS knockout (KO) 293T cells, using FUS antibody (A5921) at 1:3000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 1s.
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Immunohistochemistry of paraffin-embedded human breast cancer using FUS antibody (A5921) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded rat brain using FUS antibody (A5921) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded mouse brain using FUS antibody (A5921) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded mouse spleen using FUS antibody (A5921) at dilution of 1:100 (40x lens).
[KO Validated] FUS Rabbit pAb
Catalog No：AB-A5921
Manufacturer：ABclonal
Synonyms：FUS;ALS6;ETM4;FUS1;HNRNPP2;POMP75;TLS
Applications：WB,IHC,IF,IP
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €485,00
| Product Name: | [KO Validated] FUS Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 297-526 of human FUS (NP_004951.1). |
| Gene ID: | 2521 |
| Swiss prot: | P35637 |
| Molecular weight: | 53kDa |
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