Western blot analysis of extracts from normal (control) and EDN1 knockout (KO) HeLa cells, using EDN1 antibody (A18004) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 1min.
[KO Validated] EDN1 Rabbit pAb
Catalog No:AB-A18004
Manufacturer:ABclonal
Synonyms:EDN1;ARCND3;ET1;HDLCQ7;PPET1;QME;endothelin-1
Applications:WB,IHC,IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €485,00
Product Name: | [KO Validated] EDN1 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin/sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 18-212 of human EDN1 (NP_001946.3). |
Gene ID: | 1906 |
Swiss prot: | P05305 |
Molecular weight: | 24kDa |
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