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Western blot analysis of extracts from normal (control) and CRY1 knockout (KO) HeLa cells, using CRY1 antibody (A18028) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 10s.
[KO Validated] CRY1 Rabbit pAb
Catalog No：AB-A18028
Manufacturer：ABclonal
Synonyms：CRY1;PHLL1;DSPD
Applications：WB,IHC
Reactivity：Human,Mouse
Host：Rabbit
Conjugate：No
€65,00 – €485,00
| Product Name: | [KO Validated] CRY1 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Loss of the related gene in mouse results in a shortened circadian cycle in complete darkness. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 507-586 of human CRY1 (NP_004066.1). |
| Gene ID: | 1407 |
| Swiss prot: | Q16526 |
| Molecular weight: | 66kDa |
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