Western blot analysis of extracts from normal (control) and ATF2 Rabbit pAb knockout (KO) 293T cells, using ATF2 Rabbit pAb antibody (A2155) at 1:500 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 1s.
[KO Validated] ATF2 Rabbit pAb
Catalog No:AB-A2155
Manufacturer:ABclonal
Synonyms:CRE-BP1;CREB-2;CREB2;HB16;TREB7;ATF2
Applications:WB,IHC,IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €485,00
Product Name: | [KO Validated] ATF2 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. The encoded protein may also be involved in cell’s DNA damage response independent of its role in transcriptional regulation. Several alternatively spliced transcript variants have been found for this gene |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human ATF2 (NP_001871.2). |
Gene ID: | 1386 |
Swiss prot: | P15336 |
Molecular weight: | 13- 15kDa/23-24kDa/35-54kDa |
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