Western blot analysis of extracts of LNCaP cells, using KLK3 antibody (A2052) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 1s.
KLK3 Rabbit pAb
Catalog No:AB-A2052
Manufacturer:ABclonal
Synonyms:KLK3;APS;KLK2A1;PSA;hK3
Applications:WB,IHC,IF,IP
Reactivity:Human
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | KLK3 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human KLK3 (NP_001639.1). |
Gene ID: | 354 |
Swiss prot: | P07288 |
Molecular weight: | 7kDa/23kDa/25kDa/26kDa/28kDa |
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