Kisspeptin-13 (human)
Catalog No:CP-KISS-001A
Manufacturer:CPC Scientific
Size:1 mg
CAS No.:374675-18-0
Formula:C78H107 N21O18
MWt:1,627
€70,00
Product Name: | Kisspeptin-13 (human) |
Category: | Peptides |
Three letter sequence: | Leu-Pro-Asn- Tyr-Asn-Trp- Asn-Ser-Phe- Gly-Leu-Arg- Phe-NH2 Trifluoroacet ate salt |
One letter sequence: | LPNYNWNSFG LRF-NH2 |
Description: | An LRF-amide motif containing fragment of malignant melanoma metastasis suppressor KiSS-1. It bound with low nanomolar affinity to the rat and human G protein-coupled receptor GPR54 expressed in Chinese hamster ovary K1 cells and stimulated PIP2 hydrolysis, Ca2+ mobilization, arachidonic acid release, ERK1/2 and p38 MAP kinase phosphorylation, and stress fiber formation but inhibited cell proliferation. |
Literature References: | M.Kotani et al., J. Biol. Chem., 276, 34631 (2001) R.A.Silvestre et al., J. Endocrinol., 196, 283 (2008) |
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