KISS1 Rabbit pAb
Catalog No:AB-A2987
Manufacturer:ABclonal
Synonyms:KISS1;HH13;KiSS-1
Applications:WB,IHC
Reactivity:Human,Mouse
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | KISS1 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene is a metastasis suppressor gene that suppresses metastases of melanomas and breast carcinomas without affecting tumorigenicity. The encoded protein may inhibit chemotaxis and invasion and thereby attenuate metastasis in malignant melanomas. Studies suggest a putative role in the regulation of events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. A protein product of this gene, kisspeptin, stimulates gonadotropin-releasing hormone (GnRH)-induced gonadotropin secretion and regulates the pubertal activation of GnRH nuerons. A polymorphism in the terminal exon of this mRNA results in two protein isoforms. An adenosine present at the polymorphic site represents the third position in a stop codon. When the adenosine is absent, a downstream stop codon is utilized and the encoded protein extends for an additional seven amino acid residues. |
Immunogen: | A synthetic peptide of human KISS1 |
Gene ID: | 3814 |
Swiss prot: | Q15726 |
Molecular weight: | 14kDa |
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