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Western blot analysis of extracts of various cell lines, using Kinesin light chain 1 (Kinesin light chain 1 (KLC1)) antibody (A5552) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.
Kinesin light chain 1 (KLC1) Rabbit pAb
Catalog No：AB-A5552
Manufacturer：ABclonal
Synonyms：KLC1;KLC;KNS2;KNS2A
Applications：WB,IHC,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | Kinesin light chain 1 (KLC1) Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | Conventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, and transports various cargos along microtubules toward their plus ends. The heavy chains provide the motor activity, while the light chains bind to various cargos. This gene encodes a member of the kinesin light chain family. It associates with kinesin heavy chain through an N-terminal domain, and six tetratricopeptide repeat (TPR) motifs are thought to be involved in binding of cargos such as vesicles, mitochondria, and the Golgi complex. Thus, kinesin light chains function as adapter molecules and not motors per se. Although previously named ‘kinesin 2’, this gene is not a member of the kinesin-2 / kinesin heavy chain subfamily of kinesin motor proteins. Extensive alternative splicing produces isoforms with different C-termini that are proposed to bind to different cargos; however, the full-length nature and/or biological validity of most of these variants have not been determined. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 261-560 of human Kinesin light chain 1 (Kinesin light chain 1 (KLC1)) (NP_005543.2). |
| Gene ID: | 3831 |
| Swiss prot: | Q07866 |
| Molecular weight: | 62-72kDa |
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