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Western blot analysis of extracts of various cell lines, using KIF7 antibody (A15581) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 5s.
KIF7 Rabbit pAb
Catalog No：AB-A15581
Manufacturer：ABclonal
Synonyms：KIF7;ACLS;AGBK;HLS2;JBTS12;UNQ340
Applications：WB
Reactivity：Human
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | KIF7 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1044-1343 of human KIF7 (NP_940927.2). |
| Gene ID: | 374654 |
| Swiss prot: | Q2M1P5 |
| Molecular weight: | 150kDa |
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