ZK 756326 [Cas No. 874911-96-3]
Catalog No：TA-T3360
Manufacturer：TargetMol
Synonyms：ZK756326 2HCl
CAS No.：874911-96-3
Formula：C21H28N2O3﹞2HCl
MWt：429.38
€40,00 – €867,00
| Name: | ZK 756326 |
| Category: | Biochemicals |
| Description: | ZK 756326 is a selective, non-peptide CCR8 chemokine receptor agonist (IC50: 1.8 μM, in human, 2.6 μM, in mouse). Displays no activity at CCR4/5 and CXCR3/4 and shows higher 28-fold selectivity over 26 other GPCRs (less selective at α2A and 5-HT receptors). Induces chemotaxis and inhibits Env-mediated (HIV) cell-cell fusion. |
| Pathway: | Immunology & Inflammation, Microbiology & Virology |
| Target: | CCR agonist |
| Receptor: | CCR8 |
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