Berbamine [Cas No. 478-61-5]
Catalog No：TA-T3S0807
Manufacturer：TargetMol
CAS No.：478-61-5
Formula：C37H40N2O6
MWt：608.73
€22,00 – €313,00
| Name: | Berbamine |
| Category: | Biochemicals |
| Description: | 1. Berbamine has high binding affinity toward the (GGA),G-quadruplex. 2. Berbamine and its derivatives are promising agents to suppress liver cancer growth by targeting CAMKII. 3. Berbamine may be the first ATP-competitive inhibitor of CaMKII γ, could be as a new type of molecular targeted agent through inhibition of the CaMKII γ activity for treatment of leukemia. 4. Berbamine can enhance the antitumor activity of gemcitabine by inhibiting cell growth and inducing apoptosis, possibly through the regulation of the expression of apoptosis-related proteins and the activation of TGF-β/Smad signaling pathway. 5. Berbamine confers cardioprotection against I/R injury by attenuating [Ca(2+)inf(i) overloading and preventing calpain activation through the activation of the PI3K-Akt-GSK3β pathway and, subsequently, opening of the mitoK(ATP) channel. |
| Pathway: | Neuroscience |
| Target: | CaMKII inhibitor |
| Receptor: | CAMKIIγ |
Help & Support
Product
Guarantee and
Expert Support
Related products
Catalog No：TA-PDK0327
Manufacturer：TargetMol
CAS No.：6638-05-7
MWt：168.2
€30,00 – €50,00
Catalog No：TA-Fr16745
Manufacturer：TargetMol
CAS No.：14191-95-8
Formula：C8H7NO
MWt：133.15
€42,00 – €50,00
Catalog No：TA-Fr16605
Manufacturer：TargetMol
CAS No.：486-70-4
Formula：C10H19NO
MWt：169.3
€50,00 – €1.980,00
Catalog No：TA-Fr13711
Manufacturer：TargetMol
CAS No.：532-24-1
Formula：C8H13NO
MWt：139.19
€42,00 – €50,00
Catalog No：TA-Fr12662
Manufacturer：TargetMol
CAS No.：35817-27-7
Formula：C11H10O3
MWt：190.2
€50,00 – €90,00