Western blot analysis of extracts of various cell lines, using INHBB antibody (A8553) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 30s.
INHBB Rabbit pAb
Catalog No:AB-A8553
Manufacturer:ABclonal
Synonyms:INHBB
Applications:WB,IHC
Reactivity:Human,Mouse
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | INHBB Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | The inhibin beta B subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta B subunit forms a homodimer, activin B, and also joins with the beta A subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 293-407 of human INHBB (NP_002184.2). |
Gene ID: | 3625 |
Swiss prot: | P09529 |
Molecular weight: | 45kDa |
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