Western blot analysis of extracts of various cell lines, using IMPDH2 antibody (A15626) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 30s.
IMPDH2 Rabbit pAb
Catalog No:AB-A15626
Manufacturer:ABclonal
Synonyms:IMPDH2;IMPD2;IMPDH-II
Applications:WB,IHC
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | IMPDH2 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5′-monophosphate into xanthine-5′-monophosphate, which is then converted into guanosine-5′-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 215-514 of human IMPDH2 (NP_000875.2). |
Gene ID: | 3615 |
Swiss prot: | P12268 |
Molecular weight: | 55kDa |
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