Ile-Met-Gln- Val-Pro-Phe- Ser-Val
Catalog No:CP-CANS-004A
Manufacturer:CPC Scientific
Size:1 mg
Formula:C43H69N 9O11S1
MWt:920
€42,00
Product Name: | Ile-Met-Gln- Val-Pro-Phe- Ser-Val |
Category: | Peptides |
Three letter sequence: | Ile-Met-Gln- Val-Pro-Phe- Ser-Val |
One letter sequence: | IMQVPFSV |
Description: | Peptide that contains modified sequence of the gp 100 epitope gp(209-217), in which a methionine replaced the natural threonine at position 2. This peptide also binds to the HLA-A2 molecule with greater affinity than the unmodified peptide and has exhibited a good ability to stimulate melonomareactive cytotoxic T lymphocytes (CTLs) in vitro when used for sensitization of peripheral blood mononuclear cells. This synthetic peptide holds promise for the development of novel cancer |
Literature References: | S.A. Rosenberg et al., Nature Med., 4, 321 (1998) |
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