Western blot analysis of extracts of THP-1 cells, using IL7 antibody (A1650) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Enhanced Kit (RM00021).|Exposure time: 180s.
IL7 Rabbit pAb
Catalog No:AB-A1650
Manufacturer:ABclonal
Synonyms:IL7;IL-7
Applications:WB,IHC,IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | IL7 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | The protein encoded by this gene is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. This cytokine is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their presence in normal tissues has not been confirmed. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 26-177 of human IL7 (NP_000871.1). |
Gene ID: | 3574 |
Swiss prot: | P13232 |
Molecular weight: | 7kDa/15kDa/20kDa |
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