Western blot analysis of extracts of various cell lines, using IL21R antibody (A7468) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
IL21R Rabbit pAb
Catalog No:AB-A7468
Manufacturer:ABclonal
Synonyms:IL21R;CD360;NILR
Applications:WB
Reactivity:Human,Mouse
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | IL21R Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-240 of human IL21R (NP_851565.4). |
Gene ID: | 50615 |
Swiss prot: | Q9HBE5 |
Molecular weight: | 59kDa |
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