Western blot analysis of extracts of THP-1 cells, using IL1β antibody (A19635) at 1:1000 dilution.THP-1 cells were treated by LPS (1 μg/mL) at 37℃ for 8 hours.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 3min.
IL1β Rabbit mAb
Catalog No:AB-A19635
Manufacturer:ABclonal
Synonyms:IL-1;IL1-BETA;IL1F2;IL1 beta;IL1B
Applications:WB,IF
Reactivity:Human
Host:Rabbit
Conjugate:No
€65,00 – €485,00
Product Name: | IL1尾 Rabbit mAb |
Category: | Monoclonal Antibodies |
Description: | The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008] |
Immunogen: | A synthesized peptide derived from human IL1尾. |
Gene ID: | 3553 |
Swiss prot: | P01584 |
Molecular weight: | 17kDa |
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