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Western blot analysis of extracts of various cell lines, using IL10RA antibody (A1830) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 1s.
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Immunohistochemistry of paraffin-embedded rat brain using IL10RA Antibody (A1830) at dilution of 1:200 (40x lens).
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Immunohistochemistry of paraffin-embedded rat brain using IL10RA Antibody (A1830) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded mouse brain using IL10RA Antibody (A1830) at dilution of 1:100 (40x lens).
IL10RA Rabbit pAb
Catalog No：AB-A1830
Manufacturer：ABclonal
Synonyms：IL10RA;CD210;CD210a;CDW210A;HIL-10R;IL-10R1;IL10R
Applications：WB,IHC,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | IL10RA Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 22-230 of human IL10RA (NP_001549.2). |
| Gene ID: | 3587 |
| Swiss prot: | Q13651 |
| Molecular weight: | 63kDa |
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