Western blot analysis of extracts of various cell lines, using HP1 gamma/CBX3 Rabbit mAb (A4283) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 60s.
Western blot analysis of extracts of Rat brain, using HP1 gamma/CBX3 Rabbit mAb (A4283) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Enhanced Kit (RM00021).|Exposure time: 3min.
HP1 gamma/CBX3 Rabbit mAb
Catalog No:AB-A4283
Manufacturer:ABclonal
Synonyms:HECH, HP1-GAMMA, HP1Hs-gamma
Applications:WB,IHC
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €485,00
Product Name: | HP1 gamma/CBX3 Rabbit mAb |
Category: | Monoclonal Antibodies |
Description: | At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.[provided by RefSeq, Mar 2011] |
Immunogen: | A synthesized peptide derived from human HP1 gamma/CBX3 |
Gene ID: | 11335 |
Swiss prot: | Q13185 |
Molecular weight: | 24kDa |
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