β-Nicotinamide mononucleotide [Cas No. 1094-61-7]
Catalog No:TA-T4721
Manufacturer:TargetMol
Synonyms:β-NM
CAS No.:1094-61-7
Formula:C11H15N2O8P
MWt:334.22
€79,00 – €170,00
Name: | β-Nicotinamide mononucleotide |
Category: | Biochemicals |
Description: | Nicotinamide ribotide (NMN) is an important intermediate metabolite in the nicotinate and nicotinamide metabolism pathway. Mammals predominantly use nicotinamide rather than nicotinic acid as a precursor for NAD biosynthesis. Instead of the deamidation to nicotinic acid, nicotinamide is directly converted to NMN by nicotinamide phosphoribosyltransferase (NAMPT, EC 2.4.2.12). The enzyme nicotinamide mononucleotide adenylyltransferase (NMNAT, EC 2.7.7.1), which is a member of the nucleotidyltransferase alpha/beta-phosphodiesterase superfamily, catalyzes the reaction NMN + ATP Nicotinamide adenine dinucleotide (NAD) + PPi, representing the final step in the biosynthesis of NAD. NAD is a molecule that plays a fundamental role as a cofactor in cellular redox reactions. Thus NMN is an important metabolite for the maintenance of normal NAD biosynthesis. Circulating NMN levels may play an important role in regulating cell function in physiological and pathophysiological conditions. |
Pathway: | Others |
Target: | Others |
Receptor: | Others |
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