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Western blot analysis of extracts of various cell lines, using HMGCR antibody (A13314) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.
HMGCR Rabbit pAb
Catalog No：AB-A13314
Manufacturer：ABclonal
Synonyms：HMGCR;LDLCQ3;HMGCR
Applications：WB,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | HMGCR Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | HMG-CoA reductase is the rate-limiting enzyme for cholesterol synthesis and is regulated via a negative feedback mechanism mediated by sterols and non-sterol metabolites derived from mevalonate, the product of the reaction catalyzed by reductase. Normally in mammalian cells this enzyme is suppressed by cholesterol derived from the internalization and degradation of low density lipoprotein (LDL) via the LDL receptor. Competitive inhibitors of the reductase induce the expression of LDL receptors in the liver, which in turn increases the catabolism of plasma LDL and lowers the plasma concentration of cholesterol, an important determinant of atherosclerosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 629-888 of human HMGCR (NP_000850.1). |
| Gene ID: | 3156 |
| Swiss prot: | P04035 |
| Molecular weight: | 92kDa/97kDa/99kDa |
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Catalog No：AB-A0094
Manufacturer：ABclonal
Synonyms：CDKN2, p33(CDK2)
Applications：WB
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €485,00
Catalog No：AB-A0079
Manufacturer：ABclonal
Synonyms：FGF1;AFGF;ECGF;ECGF-beta;ECGFA;ECGFB;FGF-1;FGF-alpha;FGFA;GLIO703;HBGF-1;HBGF1
Applications：WB
Reactivity：Mouse
Host：Rabbit
Conjugate：No
€65,00 – €325,00
Catalog No：AB-A0068
Manufacturer：ABclonal
Synonyms：BCR;ALL;BCR1;CML;D22S11;D22S662;PHL
Applications：WB,IHC
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
Catalog No：AB-A0058
Manufacturer：ABclonal
Synonyms：FLT;FLT-1;VEGFR-1;VEGFR1;FLT1
Applications：WB,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
Catalog No：AB-A0064
Manufacturer：ABclonal
Synonyms：MSH2;COCA1;FCC1;HNPCC;HNPCC1;LCFS2
Applications：WB,IF
Reactivity：Human
Host：Rabbit
Conjugate：No
€245,00 – €370,00
Catalog No：AB-A0047
Manufacturer：ABclonal
Synonyms：DHQU;DIA4;DTD;NMOR1;NMORI;QR1;NQO1
Applications：WB,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00