Western blot analysis of extracts of Raji cells, using HLA-DMB antibody (A8384) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
HLA-DMB Rabbit pAb
Catalog No:AB-A8384
Manufacturer:ABclonal
Synonyms:HLA-DMB;D6S221E;RING7;major histocompatibility complex;class II;DM beta
Applications:WB,IHC
Reactivity:Human
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | HLA-DMB Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | HLA-DMB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta (DMB) chain, both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP (class II-associated invariant chain peptide) molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 19-218 of human HLA-DMB (NP_002109.2). |
Gene ID: | 3109 |
Swiss prot: | P28068 |
Molecular weight: | 28kDa |
Help & Support
Product
Guarantee and
Expert Support
Related products
Catalog No:AB-A0185
Manufacturer:ABclonal
Synonyms:GDF15;GDF-15;MIC-1;MIC1;NAG-1;PDF;PLAB;PTGFB
Applications:WB,IHC,IF,IP
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Catalog No:AB-A0166
Manufacturer:ABclonal
Synonyms:VASP
Applications:WB
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €295,00
Catalog No:AB-A0169
Manufacturer:ABclonal
Synonyms:CASP10;ALPS2;FLICE2;MCH4;caspase-10
Applications:IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Catalog No:AB-A0109
Manufacturer:ABclonal
Synonyms:D3F15S2, DNF15S2, HGFL, MSP, NF15S2
Applications:WB,IHC,IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €485,00
Catalog No:AB-A0093
Manufacturer:ABclonal
Synonyms:PRF1;FLH2;HPLH2;P1;PFN1;PFP;perforin-1;Perforin
Applications:WB,IHC,IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Catalog No:AB-A0038
Manufacturer:ABclonal
Synonyms:BRAF;B-RAF1;B-raf;BRAF1;NS7;RAFB1
Applications:WB,IHC
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00