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Western blot analysis of extracts of various cell lines, using HDAC4 Rabbit mAb (A13510) at 1：1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 3min.
HDAC4 Rabbit mAb
Catalog No：AB-A13510
Manufacturer：ABclonal
Synonyms：AHO3, BDMR, HA6116, HD4, HDAC-4, HDAC-A, HDACA
Applications：WB
Reactivity：Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €485,00
| Product Name: | HDAC4 Rabbit mAb |
| Category: | Monoclonal Antibodies |
| Description: | Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008] |
| Immunogen: | A synthesized peptide derived from human HDAC4 |
| Gene ID: | 9759 |
| Swiss prot: | P56524 |
| Molecular weight: | 140kDa |
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