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Western blot analysis of extracts of various cell lines, using Haptoglobin (Haptoglobin (HP)) antibody (A1571) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution._Lysates/proteins: 25ug per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (RM00021)._Exposure time: 90s.
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Immunohistochemistry of paraffin-embedded rat liver using Haptoglobin (Haptoglobin (HP)) antibody (A1571) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded human liver cancer using Haptoglobin (Haptoglobin (HP)) antibody (A1571) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded mouse liver using Haptoglobin (Haptoglobin (HP)) antibody (A1571) at dilution of 1:100 (40x lens).
Haptoglobin (HP) Rabbit pAb
Catalog No：AB-A1571
Manufacturer：ABclonal
Synonyms：HP;BP;HP2ALPHA2;HPA1S
Applications：WB,IHC
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | Haptoglobin (HP) Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia. This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohn’s disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinson’s disease, and a reduced incidence of Plasmodium falciparum malaria. The protein encoded also exhibits antimicrobial activity against bacteria. A similar duplicated gene is located next to this gene on chromosome 16. Multiple transcript variants encoding different isoforms have been found for this gene. |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Haptoglobin (Haptoglobin (HP)) (NP_005134.1). |
| Gene ID: | 3240 |
| Swiss prot: | P00738 |
| Molecular weight: | 38kDa/45kDa |
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