GYPB Rabbit pAb
Catalog No:AB-A15063
Manufacturer:ABclonal
Synonyms:GYPB;CD235b;GPB;GYP;MNS;PAS-3;SS
Applications:IF
Reactivity:Human
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | GYPB Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. GYPB gene consists of 5 exons and has 97% sequence homology with GYPA from the 5′ UTR to the coding sequence encoding the first 45 amino acids. In addition to the M or N and S or s antigens, that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta; also, Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are the result of gene recombinations between GYPA and GYPB. Alternate splicing results in multiple transcript variants. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-91 of human GYPB (NP_002091.3). |
Gene ID: | 2994 |
Swiss prot: | P06028 |
Molecular weight: | 6kDa/9kDa |
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