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Western blot analysis of extracts of various cell lines, using GUCY2D antibody (A3605) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
GUCY2D Rabbit pAb
Catalog No：AB-A3605
Manufacturer：ABclonal
Synonyms：GUCY2D;CORD5;CORD6;CYGD;GUC1A4;GUC2D;LCA;LCA1;RCD2;RETGC-1;ROS-GC1;ROSGC;retGC
Applications：WB
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | GUCY2D Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes a retina-specific guanylate cyclase, which is a member of the membrane guanylyl cyclase family. Like other membrane guanylyl cyclases, this enzyme has a hydrophobic amino-terminal signal sequence followed by a large extracellular domain, a single membrane spanning domain, a kinase homology domain, and a guanylyl cyclase catalytic domain. In contrast to other membrane guanylyl cyclases, this enzyme is not activated by natriuretic peptides. Mutations in this gene result in Leber congenital amaurosis and cone-rod dystrophy-6 diseases. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 52-350 of human GUCY2D (NP_000171.1). |
| Gene ID: | 3000 |
| Swiss prot: | Q02846 |
| Molecular weight: | 120kDa |
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