Shogaol [Cas No. 555-66-8]
Catalog No:TA-T6S1699
Manufacturer:TargetMol
Synonyms:[6]-Shogaol,Shogaol
CAS No.:555-66-8
Formula:C17H24O3
MWt:276.37
€31,00 – €476,00
Name: | 6-Shogaol |
Category: | Biochemicals |
Description: | 1. 6-Shogaol has antipyretic and analgesic effects in addition to inhibitory effect on lipoxygenase activity. 2. 6-shogaol has anti-inflammatory property, reduces the inflammatory response and protected the femoral cartilage from damage produced in a CFA monoarthritic model of the knee joint of rats. 3. 6-Shogaol inhibits the growth of human cancer cells and induces apoptosis in COLO 25 cells through modulation of mitochondrial functions regulated by reactive oxygen species (ROS). 4. 6-Shogaol effectively inhibit invasion and metastasis of hepatocellular carcinoma through diverse molecular mechanisms, including inhibition of the MAPK and PI3k/Akt pathways and NF-κB and STAT3 activities to suppress expression of MMP-2/-9 and uPA and block angiogenesis, could further regulate urokinase-type plasminogen activity. |
Pathway: | Metabolism,Immunology & Inflammation |
Target: | Lipoxygenase |
Receptor: | LOX |
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