(Rac)-SAR131675 [Cas No. 1092539-44-0]
Catalog No：TA-T3691
Manufacturer：TargetMol
CAS No.：1092539-44-0
Formula：C18H22N4O4
MWt：358.16
€50,00 – €324,00
| Name: | SAR131675 |
| Category: | Biochemicals |
| Description: | SAR131675 is an effective and specific VEGFR-3 inhibitor. It inhibited VEGFR-3 tyrosine kinase activity (IC50: 20 nmol/L) and VEGFR-3 autophosphorylation (IC50: 45 nmol/L) in HEK cells, respectively. SAR131675 is highly specific for VEGFR-3 versus 107 receptors, enzymes, ion channels, and 65 kinases. SAR131675 is a highly specific VEGFR-3-TK inhibitor with significant antitumoral and antimetastatic activities in vivo through inhibition of lymphangiogenesis and TAM invasion. |
| Pathway: | Angiogenesis, Tyrosine Kinase/Adaptors |
| Target: | VEGFR inhibitor |
| Receptor: | VEGFR3 |
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