Glucagon-Like Peptide I (7- 36), amide, human
Catalog No:CP-GLUC-010B
Manufacturer:CPC Scientific
Size:1 mg
CAS No.:[107444-51-9]
Formula:C149H226 N40O45
MWt:3,298
€113,00
Product Name: | Glucagon-Like Peptide I (7- 36), amide, human |
Category: | Peptides |
Three letter sequence: | His-Ala-Glu- Gly-Thr-Phe- Thr-Ser-Asp- Val-Ser-Ser- Tyr-Leu-Glu- Gly-Gln-Ala- Ala-Lys-Glu- Phe-Ile-Ala- Trp-Leu-Val- Lys-Gly-Arg- NH2 |
One letter sequence: | HAEGTFTSDVS SYLEGQAAKEF IAWLVKGR- NH2 |
Description: | GLp-1 fragment that is isolated from the lower small intestine and is presently regarded to be the most important incretin hormone. It shows a strong insulinotropic effect that is mediated by receptors expressed in the pancreatic 尾- cells. It is proposed to be a novel therapeutic strategy for non-insulin- dependent (type 2) diabetes mellitus and associated neuropathy. |
Literature References: | G. Bell et al., Nature, 304, 368 (1983) |
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