Western blot analysis of extracts of various cell lines, using GLRB antibody (A10505) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 10s.
GLRB Rabbit pAb
Catalog No:AB-A10505
Manufacturer:ABclonal
Synonyms:GLRB;HKPX2
Applications:WB
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | GLRB Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes the beta subunit of the glycine receptor, which is a pentamer composed of alpha and beta subunits. The receptor functions as a neurotransmitter-gated ion channel, which produces hyperpolarization via increased chloride conductance due to the binding of glycine to the receptor. Mutations in this gene cause startle disease, also known as hereditary hyperekplexia or congenital stiff-person syndrome, a disease characterized by muscular rigidity. Alternative splicing results in multiple transcript variants. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 23-265 of human GLRB (NP_000815.1). |
Gene ID: | 2743 |
Swiss prot: | P48167 |
Molecular weight: | 34kDa/56kDa |
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