Western blot analysis of extracts of Jurkat cells, using Gemin 2 antibody (A3082) at 1:500 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
Gemin 2 Rabbit pAb
Catalog No:AB-A3082
Manufacturer:ABclonal
Synonyms:GEMIN2;SIP1;SIP1-delta
Applications:WB,IHC,IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | Gemin 2 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes one of the proteins found in the SMN complex, which consists of several gemin proteins and the protein known as the survival of motor neuron protein. The SMN complex is localized to a subnuclear compartment called gems (gemini of coiled bodies) and is required for assembly of spliceosomal snRNPs and for pre-mRNA splicing. This protein interacts directly with the survival of motor neuron protein and it is required for formation of the SMN complex. A knockout mouse targeting the mouse homolog of this gene exhibited disrupted snRNP assembly and motor neuron degeneration. |
Immunogen: | A synthetic peptide of human Gemin 2 |
Gene ID: | 8487 |
Swiss prot: | O14893 |
Molecular weight: | 4kDa/28kDa/29kDa/31kDa |
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