FRET substrate for lasmepsin
Catalog No:CP-MALA-001B
Manufacturer:CPC Scientific
Size:5 mg
CAS No.:263718-22-5
Formula:C76H98N 16O15S
MWt:1,508
€1.118,00
Product Name: | FRET substrate for lasmepsin |
Category: | Peptides |
Three letter sequence: | DABCYL- Glu-Arg-Nle- Phe-Leu-Ser- Phe-Pro- EDANS Trifluoroacet ate salt |
One letter sequence: | ERNleFLSFP |
Description: | Useful FRET substrate for a continuous fluorescence-based assay of the malaria aspartyl protease (plasmepsin). The peptide sequence ERNleFLSFP is derived from the cleavage site present in hemoglobin, with Nle as a substitution for Met to avoid potential oxidation related problems. |
Literature References: | M.Pennington et al., Innovation and Perspectives in Solid Phase Synthesis &Combinatorial Libraries, 5th International Symposium, London, p. 367, R.Epton, ed., Mayflower Scientific, (1998) S.Jiang et al., Antimicrob. Agents Chemother., 45, 2577 (2001) M.Stadler et al., J. Antibiot., 58, 775 (2005) |
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