Ebselen [Cas No. 60940-34-3]
Catalog No：TA-T0825
Manufacturer：TargetMol
Synonyms：CCG-39161,PZ-51,SPI-1005
CAS No.：60940-34-3
Formula：C13H9NOSe
MWt：274.18
€36,00 – €342,00
| Name: | Ebselen |
| Category: | Biochemicals |
| Description: | Ebselen is a organoselenium compound with anti-inflammatory, anti-oxidant and cytoprotective activity. Ebselen acts as a glutathione peroxidase mimetic and is thereby able to prevent cellular damage induced by reactive oxygen species (ROS). In addition, this agent inhibits the activity of a variety of enzymes including nitric oxide synthase (NOS), 5-lipoxygenase, cyclooxygenase, protein kinase C (PKC), NADPH oxidase and gastric H+/K+-ATPase. Furthermore, ebselen may be neuroprotective due to its ability to neutralize free radicals upon NMDA receptor activation thus, reducing lipoperoxidation mediated by glutamate-induced excitotoxicity. |
| Pathway: | Immunology & Inflammation, Neuroscience |
| Target: | COX inhibitor |
| Receptor: | COX |
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