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Immunohistochemistry of paraffin-embedded rat spleen using FGFR2 antibody (A2074) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded human placenta using FGFR2 antibody (A2074) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded mouse heart using FGFR2 antibody (A2074) at dilution of 1:100 (40x lens).
FGFR2 Rabbit pAb
Catalog No：AB-A2074
Manufacturer：ABclonal
Synonyms：BBDS;BEK;BFR-1;CD332;CEK3;CFD1;ECT1;JWS;K-SAM;KGFR;TK14;TK25;FGFR2
Applications：IHC
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | FGFR2 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform. Mutations in this gene are associated with Crouzon syndrome, Pfeiffer syndrome, Craniosynostosis, Apert syndrome, Jackson-Weiss syndrome, Beare-Stevenson cutis gyrata syndrome, Saethre-Chotzen syndrome, and syndromic craniosynostosis. Multiple alternatively spliced transcript variants encoding different isoforms have been noted for this gene. |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human FGFR2 (NP_000132.3). |
| Gene ID: | 2263 |
| Swiss prot: | P21802 |
| Molecular weight: | 28kDa/40kDa/76-92kDa |
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