Ruscogenin [Cas No. 472-11-7]
Catalog No:TA-T6S1256
Manufacturer:TargetMol
CAS No.:472-11-7
Formula:C27H42O4
MWt:430.62
€36,00 – €433,00
Name: | Ruscogenin |
Category: | Biochemicals |
Description: | 1. Ruscogenin has anti-inflammatory activity, suppressed zymosan A-evoked peritoneal total leukocyte migration in mice in a dose-dependent manner, 2. Ruscogenin inhibited adhesion of leukocytes to a human umbilical vein endothelial cell line (ECV34) injured by tumor necrosis factor-alpha (TNF-alpha) in a concentration-dependent manner. 3. Ruscogenin significantly attenuate LPS-induced acute lung injury via inhibiting expressions of TF and iNOS and NF-kappa B p65 activation. |
Pathway: | Immunology & Inflammation,NF-κB |
Target: | NOS,NF-κB |
Receptor: | iNOS,NF-κB |
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